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Testosterone treatment fails to accelerate disease in a transgenic mouse model of spinal and bulbar muscular atrophy

SUMMARY Evidence from multiple animal models demonstrates that testosterone plays a crucial role in the progression of symptoms in spinal and bulbar muscular atrophy (SBMA), a condition that results in neurodegeneration and muscle atrophy in affected men. Mice bearing a transgene encoding a human an...

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Autors principals: Erica S. Chevalier-Larsen, Diane E. Merry
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2012-01-01
Col·lecció:Disease Models & Mechanisms
Accés en línia:http://dmm.biologists.org/content/5/1/141
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