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N-terminal region of gelsolin induces apoptosis of activated hepatic stellate cells by a caspase-dependent mechanism.

Activated hepatic stellate cells (HSCs) are the major source for alteration of extracellular matrix in fibrosis and cirrhosis. Conditioned medium (CM) collected from immortalized human hepatocytes (IHH) have earlier been shown to be responsible for apoptosis of HSCs. In this study, we have shown tha...

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Príomhchruthaitheoirí: Budhaditya Mazumdar, Keith Meyer, Ranjit Ray
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2012-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC3430645?pdf=render
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