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NS1 Protein of Influenza A Virus Down-Regulates Apoptosis

Wild-type (WT) influenza A/PR/8/34 virus and its variant lacking the NS1 gene (delNS1) have been compared for their ability to mediate apoptosis in cultured cells and chicken embryos. Cell morphology, fragmentation of chromatin DNA, and caspase-dependent cleavage of the viral NP protein have been us...

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Autori principali: Zhirnov, O. P., Konakova, T. E., Wolff, T., Klenk, H.-D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC135891/
https://ncbi.nlm.nih.gov/pubmed/11799156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.4.1617-1625.2002
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