Enhanced strand transfer and mismatch extension by HIV-1C reverse transcriptase promote sequence motif duplication

ABSTRACT Genetic diversification of HIV-1 is driven largely by the error-prone activity of reverse transcriptase (RT) and the high frequency of template switching during reverse transcription. A rare consequence of nonhomologous recombination is sequence motif duplication, which can alter viral gene...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Arun Panchapakesan, Aditya Pradeepbhai Joshi, Afzal Amanullah, Neelam Pargain, Kavita Mehta, Manisenthil Shanmugam, Jayendra Singh, Chhavi Saini, Narendra Nala, Udupi A. Ramagopal, Udaykumar Ranga
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2026-06-01
Serie:	Journal of Virology
Soggetti:	HIV-1C reverse transcriptase nonhomologous recombination sequence duplication
Accesso online:	https://journals.asm.org/doi/10.1128/jvi.00526-26
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!