Enhanced strand transfer and mismatch extension by HIV-1C reverse transcriptase promote sequence motif duplication

ABSTRACT Genetic diversification of HIV-1 is driven largely by the error-prone activity of reverse transcriptase (RT) and the high frequency of template switching during reverse transcription. A rare consequence of nonhomologous recombination is sequence motif duplication, which can alter viral gene...

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Auteurs principaux:	Arun Panchapakesan, Aditya Pradeepbhai Joshi, Afzal Amanullah, Neelam Pargain, Kavita Mehta, Manisenthil Shanmugam, Jayendra Singh, Chhavi Saini, Narendra Nala, Udupi A. Ramagopal, Udaykumar Ranga
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology 2026-06-01
Collection:	Journal of Virology
Sujets:	HIV-1C reverse transcriptase nonhomologous recombination sequence duplication
Accès en ligne:	https://journals.asm.org/doi/10.1128/jvi.00526-26
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