Enhanced strand transfer and mismatch extension by HIV-1C reverse transcriptase promote sequence motif duplication
ABSTRACT Genetic diversification of HIV-1 is driven largely by the error-prone activity of reverse transcriptase (RT) and the high frequency of template switching during reverse transcription. A rare consequence of nonhomologous recombination is sequence motif duplication, which can alter viral gene...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2026-06-01
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| Serija: | Journal of Virology |
| Teme: | |
| Online dostop: | https://journals.asm.org/doi/10.1128/jvi.00526-26 |
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