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Spray-freeze-drying aprepitant with hydroxypropyl cellulose increases nasal bioavailability

The design of free-flowing lyophilized powders by spray-freeze-drying (SFD) enables novel therapeutic applications, including nasal administration. In this study, a non-aqueous SFD approach using dimethyl sulfoxide (DMSO) as the spray solvent was investigated. Low-viscosity hydroxypropyl cellulose g...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Annika Rautenberg, Paul Bühlbecker, Jan Kožák, Claire Chrétien, Yann Pellequer, Klaus Wunderling, Edmont Stoyanov, Alexander Pfeifer, Alf Lamprecht
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2026-06-01
Rangatū:International Journal of Pharmaceutics: X
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S259015672600071X
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