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Reducing the Periplasmic Glutathione Content Makes Escherichia coli Resistant to Trimethoprim and Other Antimicrobial Drugs

ABSTRACT Although glutathione (GSH) has been shown to influence the antimicrobial effects of many kinds of antibiotics, little is known about its role in relation to trimethoprim (TMP), a widely used antifolate. In this study, several genes related to glutathione metabolism were deleted in different...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yajing Song, Zhen Zhou, Jing Gu, Junmei Yang, Jiaoyu Deng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2021-12-01
Saila:Microbiology Spectrum
Gaiak:
Sarrera elektronikoa:https://journals.asm.org/doi/10.1128/Spectrum.00743-21
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