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Periplasmic synthesis and purification of the human prolactin antagonist Δ1-11-G129R-hPRL

Abstract The human prolactin antagonist Δ1-11-G129R-hPRL is a 21.9 kDa recombinant protein with 188 amino acids that downregulates the proliferation of a variety of cells expressing prolactin receptors. Periplasmic expression of recombinant proteins in E. coli has been considered an option for obtai...

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Bibliografiske detaljer
Principais autores: Miriam F. Suzuki, Larissa A. Almeida, Stephanie A. Pomin, Felipe D. Silva, Renan P. Freire, João E. Oliveira, Regina Affonso, Carlos R. J. Soares, Paolo Bartolini
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2021-04-01
Serier:AMB Express
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Online adgang:https://doi.org/10.1186/s13568-021-01209-5
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