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Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice

Ingestion of arsenic interferes with spermatogenesis and increases the risk of male infertility, but the underlying mechanism remines unclear. In this study, we investigated spermatogenic injury with a focus on blood-testis barrier (BTB) disruption by administrating 5 mg/L and 15 mg/L arsenic orally...

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Principais autores: Xiujuan Li, Wenting Wang, Yue Hou, Gexuan Li, Huilan Yi, Shuo Cui, Juan Zhang, Xiaohong He, Hong Zhao, Zeyu Yang, Yulan Qiu, Zhizhen Liu, Jun Xie
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2023-06-01
Series:Ecotoxicology and Environmental Safety
Assuntos:
Arsenic
Sertoli cells
BTB junctional proteins
Actin filaments
Rictor/mTORC2
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0147651323004189
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