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Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26

The recent outbreak of pneumonia-causing COVID-19 in China is an urgent global public health issue with an increase in mortality and morbidity. Here we report our modelled homo-trimer structure of COVID-19 spike glycoprotein in both closed (ligand-free) and open (ligand-bound) conformation, which is...

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Principais autores: Naveen Vankadari, Jacqueline A. Wilce
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2020-01-01
Serier:Emerging Microbes and Infections
Fag:
Coronavirus
CD26
glycosylation
DPP4
spike glycoprotein
docking
Online adgang:https://www.tandfonline.com/doi/10.1080/22221751.2020.1739565
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