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Mutations in the Receptor Binding Domain of Severe Acute Respiratory Coronavirus-2 Omicron Variant Spike Protein Significantly Stabilizes Its Conformation

The Omicron variant and its sub-lineages are the only current circulating SARS-CoV-2 viruses worldwide. In this study, the conformational stability of the isolated Receptor Binding Domain (RBD) of Omicron’s spike protein is examined in detail. The parent Omicron lineage has over ten mutations in the...

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Hoofdauteur: Michael H. Peters
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2024-06-01
Reeks:Viruses
Onderwerpen:
SARS-CoV-2
coronavirus
spike protein
Omicron
receptor binding domain
conformational stability
Online toegang:https://www.mdpi.com/1999-4915/16/6/912
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