Aging-associated transcriptional programs in T cells signify constituents of TGF-β signaling for immunosenescence
Abstract Background Immunosenescence, particularly the altered ratio of naïve and memory T cells, contributes to a diminished immune reserve and impaired adaptive immunity in aging and frail populations. The role of TGF-β signaling pathway—a critical hallmark of organismal senescence and T-cell exha...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2025-12-01
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| Серія: | BMC Biology |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s12915-025-02484-5 |
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