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Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity

Homologous recombination is initiated by nucleolytic degradation (resection) of DNA double-strand breaks (DSBs), which involves different nucleases including the Mre11-Rad50-Xrs2 (MRX) complex and the Exonuclease 1 (Exo1). The characterization of a novel mutation in Mre11 causing accelerated DSB res...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Elisa Gobbini, Jacopo Vertemara, Maria Pia Longhese
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis Group 2018-09-01
Rangatū:Molecular & Cellular Oncology
Ngā marau:
Urunga tuihono:http://dx.doi.org/10.1080/23723556.2018.1511208
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