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Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing over During Double-Strand Break Repair

DNA double-strand breaks (DSBs) are one of the most deleterious types of lesions to the genome. Synthesis-dependent strand annealing (SDSA) is thought to be a major pathway of DSB repair, but direct tests of this model have only been conducted in budding yeast and Drosophila. To better understand th...

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Hlavní autoři: Grzegorz Zapotoczny, Jeff Sekelsky
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017-04-01
Edice:G3: Genes, Genomes, Genetics
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On-line přístup:http://g3journal.org/lookup/doi/10.1534/g3.116.037390
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