p53-dependent chromatin relaxation is required for DNA double-strand break repair
The tumor suppressor p53, an indispensable nuclear transcription factor, plays a central role in orchestrating cellular responses when DNA damage occurs. In this study, we demonstrate that in the initial phases of DNA double-strand break (DSB) repair, p53 is rapidly recruited to sites of damage and...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
China Science Publishing & Media Ltd.
2025-02-01
|
| Schriftenreihe: | Acta Biochimica et Biophysica Sinica |
| Schlagworte: | |
| Online-Zugang: | https://www.sciengine.com/doi/10.3724/abbs.2025008 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|