p53-dependent chromatin relaxation is required for DNA double-strand break repair
The tumor suppressor p53, an indispensable nuclear transcription factor, plays a central role in orchestrating cellular responses when DNA damage occurs. In this study, we demonstrate that in the initial phases of DNA double-strand break (DSB) repair, p53 is rapidly recruited to sites of damage and...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
China Science Publishing & Media Ltd.
2025-02-01
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| coleção: | Acta Biochimica et Biophysica Sinica |
| Assuntos: | |
| Acesso em linha: | https://www.sciengine.com/doi/10.3724/abbs.2025008 |
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