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Randomized-field microwave-assisted pharmaceutical lyophilization with closed-loop control

Abstract The current lyophilization technology for biopharmaceuticals and vaccine products is capital and energy-intensive, largely due to the use of indirect, conductive heat transfer. The heat removal and input in freezing, primary drying, and secondary drying are via contact between the product a...

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Principais autores: Alina A. Alexeenko, Ahmad Darwish, Drew Strongrich, Petr Kazarin, Chanakya Patil, Cole W. Tower, Isaac S. Wheeler, Eric Munson, Qi Zhou, Vivek Narsimhan, Kyu Yoon, Steven L. Nail, Anthony Cofer, Justin Stanbro, Harshil Renawala, Daniel Roth, Francis DeMarco, Justin Griffiths, Dimitrios Peroulis
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2025-03-01
叢編:Scientific Reports
在線閱讀:https://doi.org/10.1038/s41598-025-91642-4
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