Unbiased combination screening on repurposed drugs reveals synergistic potential of copanlisib and cerivastatin against chemoresistant high-grade serous ovarian cancer

Abstract Introduction High-grade serous ovarian cancers (HGSOCs) are challenging to treat and often resistant to therapy. Despite ongoing therapeutic progress, relapse and poor outcomes remain common among both newly diagnosed and recurrent cases. Systematic high-throughput screening of clinically a...

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Váldodahkkit:	Yu Sun, Yangyang Wang, Syed Umbreen, Benjamin Pepperrell, Niamh Buckley, Paul Mullan, Ahlam Ali, Fiona Furlong
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2025-11-01
Ráidu:	Journal of Ovarian Research
Fáttát:	Drug screening Drug combinations Chemoresistant high-grade serous ovarian cancer
Liŋkkat:	https://doi.org/10.1186/s13048-025-01828-7
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