Phenothiazine-triazole hybrids with antitumor activity by targeting human farnesyltransferase
New phenothiazine-triazole hybrids 1a-j and 2a-h were synthesized and screened for their potential to inhibit human farnesyltransferase and cancer cell growth in vitro. Four points of chemical modulation were followed and allowed to establish new structure-activity relationships in this series. The...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2026-07-01
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| Serie: | Results in Chemistry |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2211715626003309 |
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