Novel c-Jun N-Terminal Kinase (JNK) Inhibitors with an 11<i>H</i>-Indeno[1,2-<i>b</i>]quinoxalin-11-one Scaffold

c-Jun N-terminal kinase (JNK) plays a central role in stress signaling pathways implicated in important pathological processes, including rheumatoid arthritis and ischemia-reperfusion injury. Therefore, inhibition of JNK is of interest for molecular targeted therapy to treat various diseases. We syn...

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Principais autores:	Serhii A. Liakhov, Igor A. Schepetkin, Olexander S. Karpenko, Hanna I. Duma, Nadiia M. Haidarzhy, Liliya N. Kirpotina, Anastasia R. Kovrizhina, Andrei I. Khlebnikov, Irina Y. Bagryanskaya, Mark T. Quinn
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-09-01
Series:	Molecules
Assuntos:	c-Jun N-terminal kinase kinase inhibitor 11<i>H</i>-indeno[1,2-<i>b</i>]quinoxalin-11-one oxime interleukin-6 nuclear factor-κB
Acceso en liña:	https://www.mdpi.com/1420-3049/26/18/5688
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