Inhibition of PKA/CREB1 pathway confers sensitivity to ferroptosis in non-small cell lung cancer

Abstract Ferroptosis is a type of regulated cell death characterized by iron accumulation and lipid peroxidation. The molecular mechanisms underlying ferroptosis regulation in non-small cell lung cancer (NSCLC) are poorly understood. In this study, we found that protein kinase A (PKA) inhibition enh...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Guangyao Shan, Guoshu Bi, Guangyin Zhao, Jiaqi Liang, Yunyi Bian, Huan Zhang, Xing Jin, Zhengyang Hu, Guangyu Yao, Hong Fan, Cheng Zhan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-11-01
Schriftenreihe:	Respiratory Research
Schlagworte:	Ferroptosis Lipid metabolism Transcription factor Non-small cell lung cancer
Online-Zugang:	https://doi.org/10.1186/s12931-023-02567-3
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!