Inhibition of PKA/CREB1 pathway confers sensitivity to ferroptosis in non-small cell lung cancer

Abstract Ferroptosis is a type of regulated cell death characterized by iron accumulation and lipid peroxidation. The molecular mechanisms underlying ferroptosis regulation in non-small cell lung cancer (NSCLC) are poorly understood. In this study, we found that protein kinase A (PKA) inhibition enh...

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Autors principals:	Guangyao Shan, Guoshu Bi, Guangyin Zhao, Jiaqi Liang, Yunyi Bian, Huan Zhang, Xing Jin, Zhengyang Hu, Guangyu Yao, Hong Fan, Cheng Zhan
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-11-01
Col·lecció:	Respiratory Research
Matèries:	Ferroptosis Lipid metabolism Transcription factor Non-small cell lung cancer
Accés en línia:	https://doi.org/10.1186/s12931-023-02567-3
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