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Incorporating mutational heterogeneity to identify genes that are enriched for synonymous mutations in cancer

Abstract Background Synonymous mutations, which change the DNA sequence but not the encoded protein sequence, can affect protein structure and function, mRNA maturation, and mRNA half-lives. The possibility that synonymous mutations might be enriched in cancer has been explored in several recent stu...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Yiyun Rao, Nabeel Ahmed, Justin Pritchard, Edward P. O’Brien
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: BMC 2023-12-01
Цуврал:BMC Bioinformatics
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1186/s12859-023-05521-8
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