Incorporating mutational heterogeneity to identify genes that are enriched for synonymous mutations in cancer
Abstract Background Synonymous mutations, which change the DNA sequence but not the encoded protein sequence, can affect protein structure and function, mRNA maturation, and mRNA half-lives. The possibility that synonymous mutations might be enriched in cancer has been explored in several recent stu...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2023-12-01
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| Serier: | BMC Bioinformatics |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s12859-023-05521-8 |
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