Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma
Abstract Background Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. Methods We explored the role of somatic synonymous mutations in m...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-04-01
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| Colecção: | BMC Medical Genomics |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12920-020-0685-2 |
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