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Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma

Abstract Background Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. Methods We explored the role of somatic synonymous mutations in m...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Di Zhang, Junfeng Xia
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2020-04-01
Sraith:BMC Medical Genomics
Ábhair:
Rochtain ar líne:http://link.springer.com/article/10.1186/s12920-020-0685-2
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