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MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn’s disease

Crohn’s disease (CD) is the chronic inflammation of the terminal ileum and colon triggered by a dysregulated immune response to bacteria, but insights into specific molecular perturbations at the critical bacteria-epithelium interface are limited. Here, we report that the membrane mucin MUC17 protec...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Elena Layunta, Sofia Jäverfelt, Fleur C. van de Koolwijk, Molly Sivertsson, Brendan Dolan, Liisa Arike, Sara I.M. Thulin, Bruce A. Vallance, Thaher Pelaseyed
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Clinical investigation 2025-02-01
Rangatū:JCI Insight
Ngā marau:
Urunga tuihono:https://doi.org/10.1172/jci.insight.181481
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