MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn’s disease
Crohn’s disease (CD) is the chronic inflammation of the terminal ileum and colon triggered by a dysregulated immune response to bacteria, but insights into specific molecular perturbations at the critical bacteria-epithelium interface are limited. Here, we report that the membrane mucin MUC17 protec...
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| Principais autores: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical investigation
2025-02-01
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| 叢編: | JCI Insight |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1172/jci.insight.181481 |
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