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Pharmacological Inhibition of Inositol Hexakisphosphate Kinase 1 Protects Mice against Obesity-Induced Bone Loss

Obesity and type II diabetes mellitus (T2DM) are prominent risk factors for secondary osteoporosis due to the negative impacts of hyperglycemia and excessive body fat on bone metabolism. While the armamentarium of anti-diabetic drugs is expanding, their negative or unknown impacts on bone metabolism...

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Principais autores: Siddaraju V. Boregowda, Manjunatha K. Nanjappa, Cori N. Booker, Jacqueline Strivelli, Valentina M. Supper, Paul S. Cooke, Donald G. Phinney
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-08-01
Serier:Biology
Fag:
diet
high fat
obesity
osteoporosis
anti-obesity drugs
inositol hexakisphosphate kinase 1
Online adgang:https://www.mdpi.com/2079-7737/11/9/1257
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