The ribosome collision sensor Hel2 functions as preventive quality control in the secretory pathway
Summary: Ribosome collision because of translational stalling is recognized as a problematic event in translation by the E3 ubiquitin ligase Hel2, leading to non-canonical subunit dissociation followed by targeting of the faulty nascent peptides for degradation. Although Hel2-mediated quality contro...
Guardat en:
| Autors principals: | , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2021-03-01
|
| Col·lecció: | Cell Reports |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2211124721001911 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|