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The ribosome collision sensor Hel2 functions as preventive quality control in the secretory pathway

Summary: Ribosome collision because of translational stalling is recognized as a problematic event in translation by the E3 ubiquitin ligase Hel2, leading to non-canonical subunit dissociation followed by targeting of the faulty nascent peptides for degradation. Although Hel2-mediated quality contro...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yoshitaka Matsuo, Toshifumi Inada
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2021-03-01
Rangatū:Cell Reports
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124721001911
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