Generation of vascularized pancreatic progenitors through co-differentiation of endoderm and mesoderm from human pluripotent stem cells

Abstract Background The simultaneous differentiation of human pluripotent stem cells (hPSCs) into both endodermal and mesodermal lineages is crucial for developing complex, vascularized tissues, yet poses significant challenges. This study explores a method for co-differentiation of mesoderm and end...

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Autori principali:	Xiaopu Sang, Junming Xu, Yihang Wang, Jingyi Li, Jiasen Xu, Xiaoni Chen, Xianjie Shi, Fenfang Wu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-12-01
Serie:	Stem Cell Research & Therapy
Soggetti:	Human pluripotent stem cells Endoderm differentiation Mesoderm differentiation Multi-lineage co-differentiation Vascularized pancreatic progenitors
Accesso online:	https://doi.org/10.1186/s13287-024-04120-5
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