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In vitro generation of human pluripotent stem cell derived lung organoids

Recent breakthroughs in 3-dimensional (3D) organoid cultures for many organ systems have led to new physiologically complex in vitro models to study human development and disease. Here, we report the step-wise differentiation of human pluripotent stem cells (hPSCs) (embryonic and induced) into lung...

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Principais autores: Briana R Dye, David R Hill, Michael AH Ferguson, Yu-Hwai Tsai, Melinda S Nagy, Rachel Dyal, James M Wells, Christopher N Mayhew, Roy Nattiv, Ophir D Klein, Eric S White, Gail H Deutsch, Jason R Spence
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2015-03-01
Colecção:eLife
Assuntos:
pluripotent stem cell
organoid
endoderm
lung
foregut
spheroid
Acesso em linha:https://elifesciences.org/articles/05098
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