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A Novel Strategy to Regulate 1-Deoxynojirimycin Production Based on Its Biosynthetic Pathway in Streptomyces lavendulae

This study characterized the biosynthetic pathway of the secondary metabolite 1-deoxynojirimycin (DNJ) from Streptomyces lavendulae. The results revealed that glucose was a preferable precursor for DNJ synthesis, and its carbon skeleton underwent a C2-N-C6 cyclization reaction during synthesis. The...

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Hlavní autoři: Hao Wu, Ye Guo, Lei Chen, Guiguang Chen, Zhiqun Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019-08-01
Edice:Frontiers in Microbiology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fmicb.2019.01968/full
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