A multifaceted approach for the development of novel Hantzsch 1,4-dihydropyridines as anticancer agents: Rational design, parallel synthesis, analysis, cytotoxicity and EGFR/HER2 inhibition studies

Dihydropyridines (DHPs) exhibit a wide range of pharmacological properties especially against cancer. In this context, a new series of 1,4-dihydropyridines were meticulously designed employing scaffold hybridization technique targeting the EGFR/HER2 receptors. The parallel synthesis of the designed...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	A.S.V.L. Sruthi, Syed Faizan, Hemant Vikram, N.G. Veena, Aishwarya Susil, Haritha Harindranath, S. Vasanth Kumar, Vasanth Kumar Shivaraju, B.R. Prashantha Kumar
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2024-01-01
سلاسل:	Results in Chemistry
الموضوعات:	Hantzsch 1,4-dihydropyridines Anticancer activity EGFR HER-2 MCF-7 Docking
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2211715624001097
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!