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Taxol crystals can masquerade as stabilized microtubules.

Taxol is a potent anti-mitotic drug used in chemotherapy, angioplastic stents, and cell biology research. By binding and stabilizing microtubules, Taxol inhibits their dynamics, crucial for cell division, motility, and survival. The drug has also been reported to induce formation of asters and bundl...

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Bibliografiske detaljer
Principais autores: Margit Foss, Buck W L Wilcox, G Bradley Alsop, Dahong Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2008-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC2194920?pdf=render
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