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An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that targets motor neurons, leading to paralysis and death within a few years of disease onset. While several genes have been linked to the inheritable, or familial, form of ALS, much less is known about the cause(s) of spora...

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Bibliografiske detaljer
Principais autores: Melissa S Rotunno, Daryl A Bosco
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013-12-01
Serier:Frontiers in Cellular Neuroscience
Fag:
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00253/full
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