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An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that targets motor neurons, leading to paralysis and death within a few years of disease onset. While several genes have been linked to the inheritable, or familial, form of ALS, much less is known about the cause(s) of spora...

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Autors principals: Melissa S Rotunno, Daryl A Bosco
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013-12-01
Col·lecció:Frontiers in Cellular Neuroscience
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Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00253/full
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