Early upregulation of cytosolic phospholipase A2α in motor neurons is induced by misfolded SOD1 in a mouse model of amyotrophic lateral sclerosis

Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal multifactorial neurodegenerative disease characterized by the selective death of motor neurons. Cytosolic phospholipase A2 alpha (cPLA2α) upregulation and activation in the spinal cord of ALS patients has been reported. We have previ...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Yafa Fetfet Malada Edelstein, Yulia Solomonov, Nurit Hadad, Leenor Alfahel, Adrian Israelson, Rachel Levy
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2021-11-01
Ráidu:	Journal of Neuroinflammation
Fáttát:	Cytosolic phospholipase A2α ALS Mutant SOD1G93A Motor neurons TNFα Misfolded SOD1
Liŋkkat:	https://doi.org/10.1186/s12974-021-02326-5
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!