Engineering Streptomyces albulus to enhance ε-poly-L-lysine production by introducing a polyphosphate kinase-mediated ATP regeneration system

Abstract Background ε-Poly-L-lysine (ε-PL) is a natural and safe food preservative that is mainly produced by filamentous and aerobic bacteria Streptomyces albulus. During ε-PL biosynthesis, a large amount of ATP is used for the polymerization of L-lysine. A shortage of intracellular ATP is one of t...

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Hlavní autoři:	Hao Yang, Daojun Zhu, Lang Kai, Liang Wang, Hongjian Zhang, Jianhua Zhang, Xusheng Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-03-01
Edice:	Microbial Cell Factories
Témata:	Polyphosphate kinase Streptomyces albulus ε-Poly-L-lysine ATP regeneration system Polyphosphate
On-line přístup:	https://doi.org/10.1186/s12934-023-02057-7
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