Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche

Abstract The cellular organization of gastrointestinal crypts is orchestrated by different cells of the stromal niche but available in vitro models fail to fully recapitulate the interplay between epithelium and stroma. Here, we establish a colon assembloid system comprising the epithelium and diver...

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Principais autores:	Manqiang Lin, Kimberly Hartl, Julian Heuberger, Giulia Beccaceci, Hilmar Berger, Hao Li, Lichao Liu, Stefanie Müllerke, Thomas Conrad, Felix Heymann, Andrew Woehler, Frank Tacke, Nikolaus Rajewsky, Michael Sigal
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2023-05-01
叢編:	Nature Communications
在線閱讀:	https://doi.org/10.1038/s41467-023-38780-3
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