Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche

Abstract The cellular organization of gastrointestinal crypts is orchestrated by different cells of the stromal niche but available in vitro models fail to fully recapitulate the interplay between epithelium and stroma. Here, we establish a colon assembloid system comprising the epithelium and diver...

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Bibliografiske detaljer

Principais autores:	Manqiang Lin, Kimberly Hartl, Julian Heuberger, Giulia Beccaceci, Hilmar Berger, Hao Li, Lichao Liu, Stefanie Müllerke, Thomas Conrad, Felix Heymann, Andrew Woehler, Frank Tacke, Nikolaus Rajewsky, Michael Sigal
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2023-05-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-023-38780-3
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