Human amnion epithelial cells induce M2 macrophage polarisation partially via M-CSF secretion but independently of extracellular vesicles in vitro

Pregnancy requires major immunomodulatory changes, both systemically and locally, as the maternal immune system needs to be modulated to tolerate the semi-allogeneic foetus. Decidual macrophages and stromal cells, but also foetal tissues are involved in this immune tolerance, for example by inducing...

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Autors principals:	Louise Zeijlon, Snehil Budhwar, Robert Lindau, Stefan Bencina, Helen Kaipe, Maria C. Jenmalm, Roberto Gramignoli, Johanna Raffetseder
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-01-01
Col·lecció:	Frontiers in Immunology
Matèries:	amnion epithelial cells extracellular vesicles human macrophage immune regulation macrophage polarisation macrophage colony-stimulating factor
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1723968/full
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