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SAM68 directs STING signaling to apoptosis in macrophages

Abstract DNA is a danger signal sensed by cGAS to engage signaling through STING to activate innate immune functions. The best-studied downstream responses to STING activation include expression of type I interferon and inflammatory genes, but STING also activates other pathways, including apoptosis...

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-д хадгалсан:
Үндсэн зохиолчид: Demi van der Horst, Naziia Kurmasheva, Mikkel H. S. Marqvorsen, Sonia Assil, Anna H. F. Rahimic, Christoph F. Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B. Iversen, Fanghui Ren, Trine I. Jensen, Ryo Narita, Vivien R. Schack, Bao-cun Zhang, Rasmus O. Bak, Claudio Sette, Robert A. Fenton, Jacob G. Mikkelsen, Søren R. Paludan, David Olagnier
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2024-03-01
Цуврал:Communications Biology
Онлайн хандалт:https://doi.org/10.1038/s42003-024-05969-1
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