Changes in the sensitivity of GABAA current rundown to drug treatments in a model of temporal lobe epilepsy

The pharmacological treatment of mesial temporal lobe epilepsy (mTLE), the most common epileptic syndrome in adults, is still unsatisfactory, as one third of the patients are or become refractory to antiepileptic agents. Refractoriness may depend upon drug-induced alterations, but the disease per se...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Pierangelo eCifelli, Eleonora ePalma, Cristina eRoseti, Gianluca eVerlengia, Michele eSimonato
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2013-07-01
Schriftenreihe:	Frontiers in Cellular Neuroscience
Schlagworte:	Hippocampus Neocortex Pilocarpine BDNF GABA levetiracetam
Online-Zugang:	http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00108/full
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