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Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions

Tuberous sclerosis complex (TSC) is a rare multi-system genetic disease characterized by several neurological disorders, the most common of which is the refractory epilepsy caused by highly epileptogenic cortical lesions. Previous studies suggest an alteration of GABAergic and glutamatergic transmis...

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Principais autores: Gabriele Ruffolo, Anand Iyer, Pierangelo Cifelli, Cristina Roseti, Angelika Mühlebner, Jackelien van Scheppingen, Theresa Scholl, Johannes A. Hainfellner, Martha Feucht, Pavel Krsek, Josef Zamecnik, Floor E. Jansen, Wim G.M. Spliet, Cristina Limatola, Eleonora Aronica, Eleonora Palma
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-11-01
coleção:Neurobiology of Disease
Assuntos:
GABAA receptor
Epilepsy
Tuberous sclerosis complex
Brain development
Oocytes
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996116301747
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