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Transcriptome Profiling of Pediatric Core Binding Factor AML.

The t(8;21) and Inv(16) translocations disrupt the normal function of core binding factors alpha (CBFA) and beta (CBFB), respectively. These translocations represent two of the most common genomic abnormalities in acute myeloid leukemia (AML) patients, occurring in approximately 25% pediatric and 15...

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Autores principales: Chih-Hao Hsu, Cu Nguyen, Chunhua Yan, Rhonda E Ries, Qing-Rong Chen, Ying Hu, Fabiana Ostronoff, Derek L Stirewalt, George Komatsoulis, Shawn Levy, Daoud Meerzaman, Soheil Meshinchi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4580636?pdf=render
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