Sec17 (α-SNAP) and an SM-tethering complex regulate the outcome of SNARE zippering in vitro and in vivo

Zippering of SNARE complexes spanning docked membranes is essential for most intracellular fusion events. Here, we explore how SNARE regulators operate on discrete zippering states. The formation of a metastable trans-complex, catalyzed by HOPS and its SM subunit Vps33, is followed by subsequent zip...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Matthew L Schwartz, Daniel P Nickerson, Braden T Lobingier, Rachael L Plemel, Mengtong Duan, Cortney G Angers, Michael Zick, Alexey J Merz
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	eLife Sciences Publications Ltd 2017-09-01
Saila:	eLife
Gaiak:	Sec1/Munc18 Vps33 HOPS Rab AP-3 lysosome
Sarrera elektronikoa:	https://elifesciences.org/articles/27396
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!