DGAT1 protects tumor from lipotoxicity, emerging as a promising metabolic target for cancer therapy
We recently demonstrated that glioblastoma, the most lethal brain cancer, upregulates diacylglycerol O-acyltransferase 1 (DGAT1) to store excess fatty acids into triglycerides to prevent lipotoxicity and promote tumor growth. Targeting DGAT1 resulted in marked tumor cell death by triggering extensiv...
Uloženo v:
| Hlavní autoři: | , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis Group
2020-11-01
|
| Edice: | Molecular & Cellular Oncology |
| Témata: | |
| On-line přístup: | http://dx.doi.org/10.1080/23723556.2020.1805257 |
| Tagy: |
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|